Medical professionals are increasingly concerned about the psychological impact of weight-loss medications like Ozempic and Wegovy, which have gained popularity in Indian urban centres including Patna and other Bihar cities. While these drugs effectively reduce appetite and promote weight loss, doctors report patients experiencing unexpected changes in emotional responses and motivation levels.
Dr Rajesh Kumar, an endocrinologist practising in Patna, explains that these medications work by mimicking hormones that regulate blood sugar and appetite. However, some patients have reported feeling emotionally flat, experiencing reduced enthusiasm for activities they previously enjoyed, and noticing changes in their social behaviour. "We're seeing patients who successfully lose weight but complain about feeling disconnected or less driven," he notes.
The phenomenon has gained attention as these drugs, originally developed for diabetes management, are increasingly prescribed off-label for weight reduction. In Bihar, where diabetes rates have risen significantly, many patients are seeking these treatments without fully understanding potential side effects beyond the commonly discussed nausea and fatigue.
Health experts emphasise the importance of comprehensive medical supervision when using such medications. The Indian Medical Association recommends thorough psychological screening before prescription and regular mental health monitoring during treatment, particularly given India's limited mental health infrastructure in tier-two and tier-three cities.